https://www.ajmns.com/index.php/journal <div align="justify">American Journal of Medical and Natural Sciences (AJMNS) is a multidisciplinary, double blind reviewed, open-access, international peer-reviewed journal which publish original and innovative research works which will significantly contribute to the advances in Medical and Natural Sciences. AJMNS publishes the Original Research articles, Reviews on current topics, Short-Communications, Letter to the Editor, Case Reports, Image challenges, Clinical Vignettes in Medical and Natural Sciences.</div> American Journal of Medical and Natural Sciences en-US American Journal of Medical and Natural Sciences 2582-6182 <p>All the articles are published in AJMNS are under Creative Commons License. Any further distribution or use of content published under CC BY-NC 4.0 must maintain attribution to the author(s) and the published article’s title, journal citation <a href="https://creativecommons.org/licenses/by-nc/4.0">Creative Commons Attribution-NonCommercial 4.0 Unported License</a>.</p> https://www.ajmns.com/index.php/journal/article/view/19 <p>Ankle sprains are a tear of the ligament of the ankle that holds the ankle in place and connects with other bones in the leg and foot. It happens when the foot twists or rolls suddenly, causing the ankle joint to move from its natural position. It was the most frequent kind of ankle injury, and the ankle was the second most often damaged body part. Ligament tears may result in swelling and bruises. Anyone, at any age, can experience it. Walking, running, jumping, landing, uneven surface or even from wearing inappropriate footwear can cause this type of injury. The incidence rate of ankle sprain among Basketball players is 16.9%. Objective: To determine the frequency of ankle sprain among basketball players and identify risk factors associated with this injury. Material And Method: This study is a cross-sectional survey in which a simple random sampling technique was used. Data was collected from the Peshawar sports complex and the Qayyum sports complex. A total of 218 Male participants were added to the study. Data was collected through a Foot and Ankle Disability Index (FADI) and FADI Sports. Significance and association were calculated by using SPSS 27.0. The demographic statistics were calculated, and a frequency table was made. Study duration was 6 months. Results: Our survey aimed to assess the Frequency and associated risk factors of ankle sprain among Basketball players in Peshawar sports complex and Qayyum sports complex. The age ranges from 18 to 35 years, with which mean age is 1.96 ± 0.805. The age (P=&lt;0.001), Pain (P=&lt;0.001), Footwear (P=&lt;0.001), Heavy work (P=&lt;0.001), Ground surface (P=0.002), Jumping (P=&lt;0.001), Landing (P=&lt;0.001), Running (P=&lt;0.001), Low impact activities (P=&lt;0.001) were found to be significantly associated with FADI and FADI Sports. The study is significant because the p-value is less than 0.5. Conclusion: The Study concluded that there was a significant association of Ankle Sprain among Professional and Non-Professional players. The professional players were affected by ankle sprain but the ratio of Non-professional players associated with Ankle sprain was quite high, which shows the hypothesis of the study to be true, because our study shows that there is a significant relation of Ankle sprain among Non-professional players with little knowledge about the game and irregularity. This study confirms that ankle sprain significantly affects the performance of Basketball players.</p> SHAH FAHAD ALI Naseer Ullah Khushbakht Idrees Samra Javed Ramsha Ali Copyright (c) 2025 Aziz Rehman https://creativecommons.org/licenses/by-nc/4.0 2025-10-23 2025-10-23 1 11 https://www.ajmns.com/index.php/journal/article/view/20 <p>Pharmacovigilance is a key component of healthcare systems worldwide, focusing on the detection, assessment, understanding, and prevention of adverse drug reactions (ADRs). The rising incidence of ADRs has underscored the necessity for active monitoring to ensure patient safety and rational drug use. Clinical pharmacists play a vital role in pharmacovigilance through the identification, documentation, evaluation, and reporting of ADRs, as well as by educating healthcare professionals and patients. Their involvement in multidisciplinary healthcare teams enhances the early detection and management of ADRs, thereby minimizing morbidity, mortality, and healthcare costs. This review highlights the importance of pharmacovigilance, outlines the essential role of clinical pharmacists in ADR monitoring and management, and discusses the challenges and future perspectives in this domain.</p> Venkata Nagaraju G Ravi Kumar Konda Copyright (c) 2025 https://creativecommons.org/licenses/by-nc/4.0 2025-10-30 2025-10-30 12 14